Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | RNF6 | contributors: - updated : 18-12-2006 |
HGNC name | ring finger protein (C3H2C3 type) 6 |
HGNC id | 10069 |
|
Location | 13q12 Physical location : 26.786.905 - 26.796.508 |
DNA |
TYPE | functioning gene |
STRUCTURE | 9.00 kb 5 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | status | provisional |
regionally located | close to marker D13S1121 oriented from telomere to centromere |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type |
constitutive of |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
|
tissue |
|
cell lineage
cell lines
| fluid/secretion
| blood | |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
| a coiled coil domain and a C terminal ring-H2 (C3H2C3) finger domain with a short KIL motif upstream of the RING domain |
conjugated | MetalloP |
HOMOLOGY |
Homologene |
FAMILY | RING finger protein family |
CATEGORY | regulatory , transcription factor , tumor suppressor |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,nucleus,chromatin/chromosome |
basic FUNCTION | potential tumor suppressor gene involved in the pathogenesis of esophageal squamous cell carcinoma. |