| basic FUNCTION
| signaling molecule inducing osteoclast formation through receptor activator of nulear receptor NFKB ligand and PTGS2 resembling to FGF2 and stimulating the proliferation of chondrocytes |
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regulate the growth plate chondrocyte proliferation, hypertrophy and cartilage vascularization necessary for endochondral ossification  |
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may play a prominent role in chondrogenesis and osteogenesis during skeletal development and growth |
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perichondrial FGF1, FGF2, FGF6, FGF7, FGF9, FGF18, FGF21, FGF22 regulate growth plate chondrogenesis |
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induction of hepatic and intestinal proliferation |
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repressing noggin gene induction and thereby increased chondrocyte gene expression and chondrogenesis by facilitating bone morphogenetic protein-dependent signals |
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required for embryonic lung alveolar development |
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FGF18 and FGFR3 are involved, possibly as partners, in the control of intestinal precursor cell proliferation |
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provided both directional and proliferative cues to chondrocytes in the developing upper respiratory tract (exerted this effect on developing chondrocytes by up-regulating SOX9 expression) |
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enhancing cell migration in response to mechanical damage |
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seems to play a role in maintenance of chondrocyte properties, although its expression was rather high in dedifferentiated chondrocytes |
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novel regulatory mechanism for FGF18 signaling involving GLG1 and DLK1 |
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epithelial FGF18 signaling and its reduction in the milieu of hair stem cells are crucial for the maintenance of resting and growth phase, respectively |
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pleiotropic protein that stimulates proliferation in several tissues |
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could be used to improve bone repair and regeneration |
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FGF8, FGF17 and FGF18 are required for closure of the embryonic ventral body wall |
