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FLASH GENE

Symbol

KIF20A

contributors: - updated : 12-06-2003

HGNC name	kinesin family member 20A
HGNC id	9787

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

a motor domain and an ATP catalitic domain,hallmarks of kinesin like proteins,in the N terminus

HOMOLOGY

interspecies

homolog to murine Rab6kifl

Homologene

FAMILY

kinesin like protein kinase family

CATEGORY

motor/contractile , signaling , transport

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,organelle,Golgi
	intracellular,cytoplasm,cytoskeleton,microtubule,mitotic spindle
text	in later stages of mitosis,localized to the spindle mid-zone

basic FUNCTION	acting as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules
	crucial role in late anaphase B and/or cytokinesis

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

cellular trafficking transport

text	vesicular transport

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

GTP bound forms of RAB6A and RAB6B

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS