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FLASH GENE

Symbol

MAFB

contributors: npt/mct/pgu - updated : 21-03-3015

HGNC name	v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
HGNC id	6408

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

MCTO , DURS4

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral   deletion     in myeloid leukemia tumoral   translocation     specific marker for the prognostic unfavorable t(14;20) (q32;q12) in multiple myeloma patients )

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

in mafB(-/-) mice, the parathyroid did not separate from the thymus, and PTH expression and secretion were impaired