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FLASH GENE
Symbol ATP4B contributors: - updated : 25-02-2006
HGNC name ATPase, H+/K+ exchanging, beta polypeptide
HGNC id 820
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivestomach    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialabsorptive excretorydigestive epithelium  
Epithelialbarrier/lininguroepithelium  
Epithelialsecretoryglandularexocrine 
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated GlycoP
mono polymer heteromer , dimer
HOMOLOGY
interspecies homolog to murine Atp4b
homolog to C.elegans F55F3.3
Homologene
FAMILY
  • P-type cation-transporting ATPases
  • sodium/potassium Na+/K+ and hydrogen H+ ATPases beta chain family
    • CATEGORY enzyme , transport carrier
    SUBCELLULAR LOCALIZATION     plasma membrane
    text Type II membrane protein
    basic FUNCTION
  • proton pump responsible for stomach lumen acidification
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • beta subunit of gastric hydrogen/potassium H+/K+ exchanging ATPases
  • heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit
    • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS