Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | CD3E | contributors: mct - updated : 01-09-2017 |
HGNC name | CD3E antigen, epsilon polypeptide (TiT3 complex) |
HGNC id | 1674 |
|
DNA |
TYPE | functioning gene |
SPECIAL FEATURE | component of a cluster |
text | |
| |
STRUCTURE | 11.60 kb 8 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | confirmed |
Map | see CD3@ |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type |
cells |
|
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
Text | highly expresed in umbilical cord blood |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
| |
| |
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HOMOLOGY |
interspecies | ortholog to murine Cd3e |
homolog to rattus Rn.23767 | |
homolog to C.elegans B0281.5 |
Homologene |
FAMILY | immunoglobuline superfamily |
CATEGORY | regulatory , antigen , receptor membrane |
SUBCELLULAR LOCALIZATION | plasma membrane |
text | |
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basic FUNCTION | |
| |
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CELLULAR PROCESS | cell life, proliferation/growth |
PHYSIOLOGICAL PROCESS | immunity/defense |
text | positive regulation of cell proliferation |
PATHWAY |
metabolism | hormone |
signaling | signal transduction |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein | |
| |
| |
|
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | IMD18 , SCIDTE |
related resource | CD3Ebase: Mutation registry for autosomal recessive CD3epsilon immunodeficiency |
Other morbid association(s) |
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Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |
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