Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

TANK

contributors: mct/npt/pgu - updated : 02-11-2015

HGNC name	TRAF family member-associated NFKB activator
HGNC id	11562

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --over   in response to peripheral nerve injury

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed osteoarticular bone   methods for the inhibition and stimulation of TANK in osteoblasts and osteoclasts, respectively, may be a reasonable strategy to manipulate bone-destructive diseases

ANIMAL & CELL MODELS

	osteoblastogenesis was also increased in Tank-deficient mice
	Tank-/- mice spontaneously develop autoimmune glomerular nephritis in an IL6-dependent manner