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FLASH GENE
Symbol PIGL contributors: mct - updated : 11-04-2012
HGNC name phosphatidylinositol glycan, class L
HGNC id 8966
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to yeast S.cerevisiae ymb281w
Homologene
FAMILY
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,membrane
intracellular,cytoplasm,organelle,endoplasmic reticulum
basic FUNCTION
  • phosphatidylinositol glycan, class L, N-acetylglucosaminylphosphatidylinositol-N-acetylase
  • second step in glycosylphosphatidylinositol biosynthesis
  • is a zinc metalloenzyme
  • de-N-acetylase required for glycosylphosphatidylinositol (GPI) anchor formation
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component not assiciated with the GPI-GnT complex
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) CHIME
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS