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FLASH GENE
Symbol CLK1 contributors: mct/npt - updated : 07/11/2008
HGNC name CDC-like kinase 1
HGNC id 2068
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Hearing/Equilibriumear   highly
Lymphoid/Immunespleen   highly
 thymus   predominantly
Respiratoryrespiratory tracttrachea  highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
  • LAMMER family
  • carboxylate-bridged diiron family of proteins
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • may play an indirect role in governing splice site selection
  • phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm
    • CELLULAR PROCESS cell life, proliferation/growth
    nucleotide, RNA splicing
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacting with and inducing the nuclear redistribution of SR proteins SFRS* (see symbols)
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS