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FLASH GENE
Symbol CRYZL1 contributors: - updated : 03-11-2006
HGNC name crystallin, zeta (quinone reductase)-like 1
HGNC id 2420
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Digestivepharynx   predominantly
Endocrineneuroendocrinepituitary  highly
Lymphoid/Immunethymus   moderately
Nervousbrain    
Reproductivemale systemprostate  highly
 male systemtestis  moderately
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / hematopoieticbone marrow  moderately
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a conserved NAD(P)H binding site
    • HOMOLOGY
    interspecies homolog to murine Cryzl1 (90.8 pc)
    homolog to rattus Cryzl1 (89.4 pc)
    homolog to chicken CRYZL1 (79.1 pc)
    Homologene
    FAMILY
  • zinc-containing alcohol dehydrogenase family
  • quinone oxidoreductase subfamily
    • CATEGORY enzyme , structural protein
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • having an NADPH : quinone oxidoreductase activity
  • contributing to the refractive index and transparency of lens
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Zn2+
    • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS