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FLASH GENE
Symbol IL1RL2 contributors: mct - updated : 24-11-2017
HGNC name interleukin 1 receptor-like 2
HGNC id 5999
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
TIR domain (Toll-interleukin1-resistance)
HOMOLOGY
interspecies homolog to murine Il1rl2
intraspecies homolog to interleukin 1 receptor protein 2
Homologene
FAMILY
CATEGORY receptor
SUBCELLULAR LOCALIZATION     plasma membrane
basic FUNCTION unknown
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule
protein
cell & other
REGULATION
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional     --low  
ILR1L2 expression was significantly decreased in in Hirschsprung's disease (HSCR) specimens compared to controls
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS