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FLASH GENE

Symbol

DDX6

contributors: mct - updated : 08-10-2019

HGNC name	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6
HGNC id	2747

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

IDDF

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in intestine, colon, rectum adenocarcinomas tumoral   translocation     translocated in B-cell lymphoma, RCK gene (RC-K8 cell line) target of the translocation t(11;14)(q23;q32) constitutional     --over   in hepatitis C virus-related chronic hepatitis constitutional     --low   under hypoxia contributes to the activation of VEGFA expression and promotes its proangiogenic function

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS