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FLASH GENE

Symbol

GPR55

contributors: mct - updated : 18-08-2011

HGNC name	G protein-coupled receptor 55
HGNC id	4511

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --other   aberrantly expressed in several prostate and ovarian cancer cell lines, both at the mRNA and at the protein level (it has a critical role in regulating proliferation and anchorage-independent growth)

Susceptibility

to anorexia nervosa

Variant & Polymorphism other	low-functioning Val195 allele of GPR55 appears to be a risk factor for anorexia nervosa

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer     potential therapeutic target miscelleaneous pain   manipulation of GPR55 may have therapeutic potential in the treatment of both inflammatory and neuropathic pain

ANIMAL & CELL MODELS