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FLASH GENE
Symbol BCL10 contributors: mct - updated : 14-10-2016
HGNC name B-cell CLL/lymphoma 10
HGNC id 989
ASSOCIATED DISORDERS
corresponding disease(s) MALTL , IMD37
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral   translocation    
t (1;14)(p22;q32) as uncommon but recurrent events in MALT lymphoma
tumoral   deletion    
involving 1, 10, 17 chromosome in Sezary syndrome and chromosome instability
tumoral fusion      
an IGH-BCL2-fusion with t(1;14)(p22;q32), in MALT lymphoma
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
Bcl 10-/- mice (Ruland 01)