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FLASH GENE

Symbol

LRP6

contributors: mct - updated : 02-06-2017

HGNC name	low density lipoprotein receptor-related protein 6
HGNC id	6698

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

in Lrp6 mutant mice, the mechanism of birth defect prevention by Folic acid supplementation (reduction of neural tube defects occurrence by amelioration versus increased embryonic loss) can vary not only with the genes associated with increased risk, but also with the type of mutation within those genes (i.e. loss or gain of function )