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FLASH GENE
Symbol IHPK1 contributors: mct/npt - updated : 15/10/2008
HGNC name inositol hexaphosphate kinase 1
HGNC id 18360
Location 3p21.31      Physical location : -
Synonym name
  • Pi uptake stimulator
  • inositol hexakisphosphate kinase 1
  • ATP:1D-myo-inositol-hexakisphosphate phosphotransferase
  • InsP6 kinase 1
  • Synonym symbol(s) IP6K1, KIAA0263, INSP6K1, MGC9925, PiUS
    EC.number 2.7.4.21
    DNA
    TYPE functioning gene
    SPECIAL FEATURE arranged in tandem
    STRUCTURE 62.25 kb     6 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked   status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    6 - 4468 50.1 441 - Kamimura (2004)
    5 - 4117 31.4 276 - Kamimura (2004)
    EXPRESSION
    Type ubiquitous
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Hearing/Equilibriumear   highly
    Lymphoid/Immunespleen   highly
    Nervousbrain    
     nerve   highly
    Urinarykidney    
    Visualeye    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / Hematopoieticbone marrow   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    HOMOLOGY
    Homologene
    FAMILY
  • inositol phosphokinase (IPK) family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    intracellular,nucleus
    basic FUNCTION
  • may be acting as energy reserves in selected intracellular sites
  • regulating chromatin remodeling and transcription
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    constitutional   deletion    
    associated to defect of inositol pyrophosphate regulation, of insulin secretion, growth, and spermiogenesis
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS