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FLASH GENE

Symbol

VAMP8

contributors: mct/pgu - updated : 20-06-2016

HGNC name	vesicle-associated membrane protein 8 (endobrevin)
HGNC id	12647

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	VAMP8 null mice resulted in hydronephrosis and the level of AQP2 was increased by 3 to 5fold. VAMP8 may mediate the regulated fusion of AQP2-positive vesicles with the plasma membrane
	VAMP8 null mice display reduced adiposity with increased energy expenditure despite normal food intake and reduced spontaneous locomotor activity