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FLASH GENE

Symbol

GIPC1

contributors: mct - updated : 31-08-2020

HGNC name	GIPC PDZ domain containing family, member 1
HGNC id	1226

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

OPDM2

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   overexpressed in breast and ovarian cancer , tumoral     --low   in gastric, colorectal cancer, primary kidney and prostate tumors

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

Gipc1 mutant mice show specific defects in axonal projections, as well as vascular structures, that rely on Plexin-D1 signalling for their development