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FLASH GENE
Symbol DGKI contributors: mct/npt - updated : 08/12/2008
HGNC name diacylglycerol kinase, iota
HGNC id 2855
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two cysteine-rich repeats
  • protein kinase conserved region 1 C1
  • a conserved DAG catalytic domain
  • a DAG accessory domain
  • a four ankyrin repeats at its C terminus
    • HOMOLOGY
    Homologene
    FAMILY
  • eukaryotic diacetylglycerol kinase family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION
  • converting diacylglycerol to phosphatidic acid
  • may play a crucial role in the production of phosphatidic acid in the retina
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • may attenuate protein kinase activity
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS