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FLASH GENE

Symbol

MATN4

contributors: mct - updated : 08-06-2021

HGNC name	matrilin 4
HGNC id	6910

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	FBN2, TNC, MATN2, and MATN4 may be markers of the pathogenesis of either granular or lattice type I corneal dystrophy
Therapy target

ANIMAL & CELL MODELS

Matn4-/- mice developed age-associated osteoarthritis suggesting a crucial role of MATN4 in maintaining the stability of the articular cartilage