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FLASH GENE
Symbol FZD7 contributors: mct/ - updated : 10-04-2013
HGNC name frizzled homolog 7 (Drosophila)
HGNC id 4045
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in primary gastric and colorectal cancer
tumoral     --low  
in colon cancer
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
  • promise as a biomarker for triple negative breast cancer
  • Therapy target
    SystemTypeDisorderPubmed
    cancerdigestivecolon
    FZD7-siRNA may be used as a therapeutic reagent for colorectal cancer
    cancerreproductivebreast
    promise as a potential therapeutic target for triple negative breast cancer
    cancer  
    targeted inhibition of FZD7 represents a rational and promising new approach for cancer therapy
    ANIMAL & CELL MODELS