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	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

IFIT3

contributors: mct - updated : 21-02-2017

HGNC name	interferon-induced protein with tetratricopeptide repeats 3
HGNC id	5411

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in aggressive pancreatic cancer cells

Susceptibility

to Chronic Obstructive Pulmonary Disease

Variant & Polymorphism other	rare SNP in IFIT3, which emerged in the meta-analysis (rs140549288) increase the risk of Chronic Obstructive Pulmonary Disease (COPD)

Candidate gene
Marker	high expression of IFIT3 was independently correlated to shorter patients survival and may serve as a prognostic marker in pancreatic ductal adenocarcinoma
Therapy target

ANIMAL & CELL MODELS