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FLASH GENE
Symbol AZU1 contributors: - updated : 04-05-2006
HGNC name azurocidin 1 (cationic antimicrobial protein 37)
HGNC id 913
Location 19p13.3      Physical location : 827.830 - 832.017
Synonym symbol(s) AZU,CAP37,AZAMP
EC.number 3.4.21.-
DNA
TYPE functioning gene
STRUCTURE 4.00 kb     5 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Map see ELA2
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoietic    
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticneutrophil
Cardiovascularendothelial cell
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer monomer
HOMOLOGY
intraspecies homolog to neutrophil and monocyte derived serine protease
Homologene
FAMILY
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytosolic,granule
text released from azurophilic granules
basic FUNCTION
  • involved in oxygen independent phagocytes of Gram- bacteria
  • important multifunctional inflammatory mediator
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    induced by by inflammatory mediators
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS