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FLASH GENE

Symbol

NOVA1

contributors: mct - updated : 31-08-2016

HGNC name	neuro-oncological ventral antigen 1
HGNC id	7886

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   in gastric tumor cells was associated with tumor progression and poor prognosis tumoral       gain of function may be involved in certain subtypes of T- and NK-cell lymphomas, but not in B-cell lymphomas

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	may act as a prognostic marker for poor outcome and high recurrence in hepatocellular carcinoma
Therapy target
	System Type Disorder Pubmed cancer reproductive breast potential therapeutic targets in breast cancer

ANIMAL & CELL MODELS

Nova1-deficient mice (Jensen,2000)