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FLASH GENE
Symbol TMEM50B contributors: mct - updated : 15-03-2011
HGNC name transmembrane protein 50B
HGNC id 1280
EXPRESSION
Rna function strong mRNA expression was seen in the cerebellum, hippocampus and olfactory bulb, with diffuse cortical expression
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinesmall intestine   
 liver    
Lymphoid/Immunespleen    
Nervousbrainhindbraincerebellum   Homo sapiens
Urinarykidney   highly
cells
SystemCellPubmedSpeciesStageRna symbol
NervousPurkinje cell Homo sapiens
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
four potentials transmembrane domains
HOMOLOGY
interspecies ortholog to murine Tmem50b
Homologene
FAMILY UPF0220 family
CATEGORY regulatory
SUBCELLULAR LOCALIZATION     plasma membrane
    intracellular
intracellular,cytoplasm,organelle,membrane
intracellular,cytoplasm,organelle,endoplasmic reticulum
intracellular,cytoplasm,organelle,Golgi
text
  • integral membrane protein
  • present on endoplasmic reticulum (ER) and Golgi apparatus membranes
  • basic FUNCTION
  • developmentally-regulated intracellular ER and Golgi apparatus membrane protein that may prove important for correct brain development through functions associated with precursor cells and glia
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS