| protein
| associates with histone H3 and centromeres at the times when histone H3 and CENP-A are phosphorylated in early G2  |
|
ras GTPase-activating protein, RasGAP |
|
baculoviral IAP repeat-containing 5, BIRC5 |
|
phosphorylates MgcRacGAP |
|
inner centromere protein, INCENP |
|
might undergo degradation by binding to PSMA3 in a proteasome-dependent manner during mitosis |
|
regulates of mitotic centromere-associated kinesin (MCAK) activity and its localization at the centromere and kinetochore |
|
transforming, acidic coiled-coil containing protein 1, TACC1 |
|
mitotic kinesin-like protein 2, MKlp2 |
|
Septin1, SEPT1 |
|
phosphorylates Histone H3 |
|
ecotropic viral integration site 5, EVI5 |
|
AURKB activity is required for the accumulation of tension-sensitive mitotic-checkpoint components, such as ZW10 and KNTC1, in order to maintain mitotic-checkpoint arrest |
|
end-binding protein 1, EB1 |
|
DSN1 is a cognate substrate of AURKB, and the phosphorylation sites were mapped to Ser-100 and Ser-109 |
|
BARD1beta |
|
Flotillin-1, FLOT1 |
|
SGOL2 is an hitherto unknown crucial cellular substrate of Aurora B in mammalian cells |
|
interrelationship between MLF1IP and NDC80 in the stabilization of kinetochore-microtubule attachment, and this interaction is under Aurora-B modulation |
|
AURKB kinase activity is required for normal chromosomal localization of the CPC, indicating an intimate linkage between AURKB and HASPIN functions in mitosis |
|
ZWINT is a novel AURKB substrate required for kinetochore assembly and for proper spindle assembly checkpoint silencing at metaphase |
|
AURKB phosphorylation antagonizes the interaction between the SKA complex and the KMN network (named according to the acronym for KNL1, MIS12, and NDC80), thereby controlling SKA recruitment to kinetochore (KT) and stabilization of KT-MT attachments |
|
CHMP4C functioned in the Aurora B–dependent abscission checkpoint to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage |
|
target of HASPIN inhibitor possibly HASPIN itself, may further contribute to spindle assembly checkpoint (SAC) signaling downstream of AURKB |
|
AURKB, which regulates KIF23 localization at the midzone, is delocalized from the spindle midzone and the midbody but not from the metaphase chromosomes upon SRC expression |
|
AURKB ensures that suppression of microtubule dynamic instability by KIF4A is restricted to a specific subset of microtubules and thereby contributes to central spindle size control in anaphase |
|
AURKB and CDK1 mediate WAPL activation and release of acetylated cohesin from chromosomes by phosphorylating CDC5A |
|
novel role for AURKB-NDC80-TTK signaling axis in governing accurate chromosome segregation in mitosis |
|
TERF1 is required for the centromeric function of AURKB, which ensures proper chromosome segregation |
|
CHEK2 stabilizes TTK and phosphorylates AURKB-serine 331 to prevent mitotic exit when most kinetochores are unattached |
|
HASPIN kinase plays a key role in maintaining the slowly exchanging centromere CDCA8pool, while AURKB play minimal role in maintaining chromosomal passenger complex (CPC) localization once cells are in mitosis |
|
the putative coiled-coil domain within INCENP drives midzone localization of AURKB via a direct, electrostatic interaction with microtubules |
|
targeting AURKB to microtubules by UBASH3B is necessary for the timing and fidelity of chromosome segregation in human cells |
|
MAD1L1 plays a minor role in influencing the MAD2L1-dependent regulation of AURKB suggesting that the effects of MAD2L1 on AURKB are independent of the spindle checkpoint complex |
|
AURKA promotes the establishment of spindle assembly checkpoint by priming the HASPIN-AURKB feedback loop in late G2 phase |
|
AURKB/AURKC) are activated by binding to the C-terminal domain of INCENP |
|
AURKB, together with IN-box, the C-terminal part of INCENP, forms an enzymatic complex that ensures faithful cell division |
