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FLASH GENE
Symbol UTF1 contributors: mlc - updated : 15-12-2007
HGNC name undifferentiated embryonic cell transcription factor 1
HGNC id 12634
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
Text pluripotent embryonic stem cells
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two highly conserved domain CD1 and CD2, independently able to bind to TATA-binding protein complex
  • a leucine zipper in CD2
    • HOMOLOGY
    interspecies homolog to murine undifferentiated embryonic cell transcription factor 1(from the F9 teratocarcinoma cell line)
    Homologene
    FAMILY
    CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • potentiating ATF-2 (activating transcription factor)-2 activity
  • displaying many of the hallmark characteristics expected for a tissue-specific transcriptional coactivator that works in early embryogenesis
    • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein Tata binding protein complex
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS