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FLASH GENE

Symbol

TNFSF10

contributors: mct - updated : 25-10-2017

HGNC name	tumor necrosis factor (ligand) superfamily, member 10
HGNC id	11925

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in low grade astrocytomas, glioblastomas

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer     potential implications for cancer therapy using TNFSF10-receptor agonists cancer     combination of WEE1 inhibitor and TNFSF10 could provide a novel combination for the treatment of basal/triple-negative breast cancer

ANIMAL & CELL MODELS