Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

Home Page

FLASH GENE

Symbol

CBFA2T3

contributors: mct/npt/pgu - updated : 31-03-2012

HGNC name	core-binding factor, runt domain, alpha subunit 2; translocated to, 3
HGNC id	1537

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral   translocation     targeted by t(16;21) in acute myeloid leukemia, and is required for hematopoietic progenitor cell fate decisions and for early progenitor cell proliferation tumoral   translocation     CBFA2T3/ACSF3 locus is a novel recurrent oncogenic target of IGH translocations, which might contribute to the pathogenesis of pediatric germinal center-derived B-cell lymphoma

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

Mice with constitutive deletion of Mtg16 display defects in hematopoietic stem/progenitor cell functions