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FLASH GENE
Symbol ARHGDIG contributors: mct/npt - updated : 09-7-2009
HGNC name Rho GDP dissociation inhibitor (GDI) gamma
HGNC id 680
PROTEIN
PHYSICAL PROPERTIES Hydrophobic
STRUCTURE
motifs/domains
  • N-terminal 30AAs hydrophobic domain (Adra 1997)
    • HOMOLOGY
    interspecies homolog to C.elegans F46H6.1
    Homologene
    FAMILY
  • Rho GDI family
    • CATEGORY signaling
    SUBCELLULAR LOCALIZATION     plasma membrane
    intracellular,cytoplasm,cytosolic,ribosome
    text associated with vesicular membranes (Wu 2009)
    basic FUNCTION
  • role in modulating the activation of GTPase by inhibiting the exchange of GDP for GTP
  • invasion and metastasis suppressor
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS