Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

Home Page

FLASH GENE

Symbol

PCDH9

contributors: mct - updated : 21-04-2020

HGNC name	protocadherin 9
HGNC id	8661

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   by methylation of the PCDH9 promoter observed in 22p100 primary hepatocellular carcinoma (HCC), associated with a larger tumor size and a more pronounced intrahepatic dissemination tumoral     --low   during the development and progression of gastric cancer

Susceptibility

to major depressive disorder (MDD)

Variant & Polymorphism SNP	rs9540720 in the PCDH9 gene was genome-wide significantly associated with MDD

Candidate gene
Marker	PCDH9 could be a promising biomarker of the gastric cancer
Therapy target
	System Type Disorder Pubmed cancer digestive liver restored PCDH9 expression could inhibit cell proliferation of HCC cell lines via inducing cell cycle arrest at G0/G1 phase

ANIMAL & CELL MODELS