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FLASH GENE
Symbol IGSF3 contributors: mct - updated : 26-02-2015
HGNC name immunoglobulin superfamily, member 3
HGNC id 5950
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • immunoglobulin-like membrane protein with eight Ig domains,a EWI (Glu-Irp-Ile domain) and an intercysteine loop
  • a potential transmembrane segment and a charged cytoplasmic tail
    • conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY immunoglobulin superfamily
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     plasma membrane
    text
  • immunoglobulin-like membrane protein
    • basic FUNCTION potentially involved in cell-surface recognition
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • SIN3A complex acts as a context-dependent ISGF3/STAT3 transcriptional switch
    • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) LCDD
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS