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FLASH GENE
Symbol IGSF3 contributors: mct - updated : 26-02-2015
HGNC name immunoglobulin superfamily, member 3
HGNC id 5950
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivefemale systemplacenta  highly Homo sapiensmRNA
Respiratorylung   highly Homo sapiensmRNA
Urinarykidney   highly Homo sapiensmRNA
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • immunoglobulin-like membrane protein with eight Ig domains,a EWI (Glu-Irp-Ile domain) and an intercysteine loop
  • a potential transmembrane segment and a charged cytoplasmic tail
    • conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY immunoglobulin superfamily
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     plasma membrane
    text
  • immunoglobulin-like membrane protein
    • basic FUNCTION potentially involved in cell-surface recognition
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • SIN3A complex acts as a context-dependent ISGF3/STAT3 transcriptional switch
    • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) LCDD
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS