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FLASH GENE

Symbol

ECM2

contributors: npt/ - updated : 03-01-2005

HGNC name	extracellular matrix protein 2, female organ and adipocyte specific
HGNC id	3154

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	9q22.3      Physical location : 95.257.598 - 95.298.252
Synonym name	matrix glycoprotein SC1/ECM2
	extracellular matrix protein 2
Synonym symbol(s)	MGC126355, MGC126356

DNA

TYPE	functioning gene
STRUCTURE	40.65 kb     10 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

confirmed

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed ECM2 10 - 3163 77.4 699 - -

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Reproductive female system ovary         female system uterus         female system breast

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Connective adipose       Epithelial secretory glandular

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	a VWFC domain
	an integrin-binding sequence (RGD)
	a leucine-rich repeat

HOMOLOGY

Homologene

FAMILY	small leucine-rich proteoglycan (SLRP) family
	class I subfamily

CATEGORY

structural protein

SUBCELLULAR LOCALIZATION

extracellular

basic FUNCTION

playing a role in cell- cell or cell- ECM recognition

CELLULAR PROCESS	cell life

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

constituent of extracellular matrix

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS