| basic FUNCTION
| bipartite protein linking with high- affinity the actin cytoskeleton and the membrane |
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including recruitment of actin and other cytoskeletal proteins into specialized structures at the plasma membrane and in the nuclei of growing cells |
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may mediate actin and myosin II filament organization at cholesterol-rich membrane domains |
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costameric protein assembling during myogenesis and contributing to myogenic membrane structure and differentiation |
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serves as a new ERK scaffolding protein and provides a mechanism for regulation of ERK binding, activation and release from the signaling complex (Gangopadhyay 2009) |
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attaches directly to the Z-line through an interaction with the nebulin C-terminus (Lee 2009) |
