basic FUNCTION
| participating in NF-kappa-B-inducing signalling cascade common to TNF/NGF receptors family and IL1R |
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involved in the constitutive activation of the alternative pathways and controlling cell proliferation in pancreatic cancer cells |
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selective role in signaling by the LTBR |
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component of the EGF/heregulin receptor signaling complexes |
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SMG1 and MAP3K14 function as critical repressors of Smac mimetic compounds-mediated apoptosis by potentially converging on the regulation of CFLAR metabolism |
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role of TRAF3 and MAP3K14 in T cell malignancies, indicating that TRAF3 differentially governs the growth of B and T cell cancers |
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non-redundant role for MAP3K14 in human immune responses, demonstrating that loss-of-function mutations in MAP3K14 can cause multiple aberrations of lymphoid immunity |