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FLASH GENE
Symbol DPYS contributors: - updated : 07-05-2007
HGNC name dihydropyrimidinase
HGNC id 3013
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
amidohydrolase domain
HOMOLOGY
interspecies homolog to murine Dpys
homolog to C.elegans c47e12.8
Homologene
FAMILY desydropyrimidinase family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION
basic FUNCTION
  • conversion of 5.6-dihydronacil to 3-ureidopropionate
  • detoxifying 5-fluorouracil
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism purine/pyrimidine
    signaling
    pyrimidine metabolism
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) DPYS
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS