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FLASH GENE
Symbol SBF1 contributors: npt/ - updated : 17-09-2004
HGNC name SET binding factor 1
HGNC id 10542
Location 22q13.33      Physical location : 50.883.432 - 50.913.464
Synonym name myotubularin related 5
Synonym symbol(s) MTMR5, DKFZp761D0422, MGC99700
EC.number 3.1.3.48
DNA
TYPE functioning gene
STRUCTURE 28.22 kb     40 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
Map cen - D22S274 - D22S1141 - D22S1170 - D22S1169 - SBF1 - qter
Authors GeneMap (98)
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
40 - 6134 208.2 1867 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
Digestiveliver    
Endocrinepancreas    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Muscularstriatumcardiac  
Muscularstriatumskeletal  
Nervouscentral   
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a region similar to the active site of tyrosine phosphatases
  • a double-helical motif similar to the SET interaction domain
  • HOMOLOGY
    Homologene
    FAMILY
  • protein-tyrosine phosphatase family
  • non-receptor class myotubularin subfamily
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • tyrosine phosphatase activity
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • SET binding domain of HRX
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS