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FLASH GENE
Symbol SBF1 contributors: npt/ - updated : 17-09-2004
HGNC name SET binding factor 1
HGNC id 10542
Location 22q13.33      Physical location : 50.883.432 - 50.913.464
Synonym name myotubularin related 5
Synonym symbol(s) MTMR5, DKFZp761D0422, MGC99700
EC.number 3.1.3.48
DNA
TYPE functioning gene
STRUCTURE 28.22 kb     40 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
Map cen - D22S274 - D22S1141 - D22S1170 - D22S1169 - SBF1 - qter
Authors GeneMap (98)
Physical map
MOV10L1 22q13.33 Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse) PANX2 22q13.33 pannexin 2 PP2447 22q13.33 hypothetical protein PP2447 SELO 22q13.33 selenoprotein O TUBGCP6 22q13.31-q13.33 tubulin, gamma complex associated protein 6 HDAC10 22q13.31 histone deacetylase 10 MAPK12 22q13.33 mitogen-activated protein kinase 12 MAPK11 22q13.33 mitogen-activated protein kinase 11 PLXNB2 22q13.31-q13.33 plexin B2 KIAA0685 22q13.3 plexin B2 SBF1 22q13.33 SET binding factor 1 FLJ21135 ALDRL6 22q13.3 aldehyde reductase (aldose reductase) like 6 BC002942 22q13.33 hypothetical protein BC002942 384D8-2 22q13.33 hypothetical protein 384D8_6 SCO2 22q13.33 SCO cytochrome oxidase deficient homolog 2 (yeast) ECGF1 22q13.3 endothelial cell growth factor 1 (platelet-derived) LOC391341 22 similar to MGC52679 protein LOC113730 22q13.33 hypothetical protein BC009980 LOC388918 22 LOC388918 CHKL-CPT1B 22q13.33 choline kinase-like, carnitine palmitoyltransferase 1B (muscle) transcription unit CPT1B 22q13.3 carnitine palmitoyltransferase 1B (muscle) CHKL 22q13.33 choline kinase-like MAPK8IP2 22q13.2-q13.33 mitogen-activated protein kinase 8 interacting protein 2 ARSA 22q13.33 arylsulfatase A SHANK3 22q13-3 SH3 and multiple ankyrin repeat domains 3
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
40 - 6134 208.2 1867 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
Digestiveliver    
Endocrinepancreas    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Muscularstriatumcardiac  
Muscularstriatumskeletal  
Nervouscentral   
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a region similar to the active site of tyrosine phosphatases
  • a double-helical motif similar to the SET interaction domain
  • HOMOLOGY
    Homologene
    FAMILY
  • protein-tyrosine phosphatase family
  • non-receptor class myotubularin subfamily
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • tyrosine phosphatase activity
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • SET binding domain of HRX
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS