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FLASH GENE

Symbol

CYP2A6

contributors: mct - updated : 24-08-2010

HGNC name	cytochrome P450, family 2, subfamily A, polypeptide 6
HGNC id	2610

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

related resource

Human Cytochrome P450 (CYP) Allele Nomenclature Committee

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional   deletion     in the poor metabolizer phenotype

Susceptibility

susceptibility factor for nicotine addiction and lung cancer to smoking behavior

Variant & Polymorphism other	CYP2A6*4C allele had lower risk of tobacco-related lung cancer
	sequence variants associated with smoking behavior (Thorgeirsson 2010)

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS