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FLASH GENE

Symbol

CBR3

contributors: npt/mct - updated : 10-09-2014

HGNC name	carbonyl reductase 3
HGNC id	1549

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

to interindividual variability in the disposition of CBR drug substrates to type 2 diabetes and insulin resistance

Variant & Polymorphism other	common CBR3 V244M polymorphism encodes for CBR3 isoforms with distinctive enzymatic properties
	rs10483032 in the CBR3 (carbonyl reductase 3) gene, associated with type 2 diabetes

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS