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FLASH GENE
Symbol CHST1 contributors: mct - updated : 20-09-2004
HGNC name carbohydrate (keratan sulfate GAL-6) sulfotransferase 1
HGNC id 1969
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a RGD sequence
HOMOLOGY
interspecies homolog to murine Chst1
homolog to Drosophila CG1332
homolog to C.elegans T01H10.8
Homologene
FAMILY
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,membrane
intracellular,cytoplasm,organelle,Golgi
text
  • Golgi membrane-bound
  • type II transmembrane protein
    • basic FUNCTION
  • its activation facilitates Schwann cell migration during axonal growth
  • maybe involved in the biosynthesis of keratan sulfate in the brain and in the cornea
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS development
    text chondrogenesis
    PATHWAY
    metabolism carbohydrate
    signaling
    polysaccharides biosynthesis of keratan sulfate in brain and cornea
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS