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FLASH GENE
Symbol CHST1 contributors: mct - updated : 20-09-2004
HGNC name carbohydrate (keratan sulfate GAL-6) sulfotransferase 1
HGNC id 1969
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularvesselsaorta  highly
Digestivemouth    
 salivary gland    
Endocrineneuroendocrinepituitary   
Nervousbrain   highly
Visualeyeanterior segmentcornea  
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialbarrier/lining   
Muscularstriatumskeletal  
cells
SystemCellPubmedSpeciesStageRna symbol
Cardiovascularendothelial cell
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a RGD sequence
HOMOLOGY
interspecies homolog to murine Chst1
homolog to Drosophila CG1332
homolog to C.elegans T01H10.8
Homologene
FAMILY
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,membrane
intracellular,cytoplasm,organelle,Golgi
text
  • Golgi membrane-bound
  • type II transmembrane protein
    • basic FUNCTION
  • its activation facilitates Schwann cell migration during axonal growth
  • maybe involved in the biosynthesis of keratan sulfate in the brain and in the cornea
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS development
    text chondrogenesis
    PATHWAY
    metabolism carbohydrate
    signaling
    polysaccharides biosynthesis of keratan sulfate in brain and cornea
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS