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FLASH GENE
Symbol BICD2 contributors: mct - updated : 22-01-2019
HGNC name bicaudal D homolog 2 (Drosophila)
HGNC id 17208
ASSOCIATED DISORDERS
corresponding disease(s) SMALED2
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
  • transgenic mice with neuron-specific expression of Bicaudal D2 N-terminus (Bicd2-N) did not develop signs of motor neuron degeneration and motor abnormalities
  • Bicd2-deficient mice develop disrupted laminar organization of cerebral cortex and the cerebellum, pointing to impaired radial neuronal migration