basic FUNCTION
| playing an essential role for normal transcription during meiosis |
|
promotes germ-cell-specific patterns of polyadenylation by binding to different downstream sequence elements |
|
CSTF2, CSTF2T differ in their affinities for specific RNA sequences, and the region C-terminal to the RBDs (RNA-binding domains) is mportant in RNA sequence recognition |
|
required not only for expression of genes involved in morphological differentiation of spermatids but also for genes having products that function during interaction of motile spermatozoa with eggs |
|
necessary for spermatogenesis and fertilization |
|
its function is primarily to support spermatogenesis, but only incidentally to support immune cell function |
|
plays likely a role in 3prime end determination and transcription termination for a large range of germ cell-expressed genes |
|
functional overlap and specificity of CSTF2, CSTF2T mRNA 3 prime processing factors and provided new insights into the regulatory mechanisms of mRNA 3 prime processing |