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FLASH GENE
Symbol SYNJ2 contributors: - updated : 03-05-2002
HGNC name synaptojanin 2
HGNC id 11504
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a SAC1 domain
  • a RNA recognition motif
  • a C terminal proline rich region
    • HOMOLOGY
    interspecies homolog to rattus synaptojanin
    homolog to murine Synj2
    homolog to C.elegans y38c9a.1
    Homologene
    FAMILY inosital-1,4,5-triphosphate 5-phosphatase family
    CATEGORY enzyme , transport
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • phosphatidylinositol-3,4,5-triphosphate 5-phosphatase
  • playing an essential role in synaptic vesicle recycling
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS endocytosis transport
    text synaptic vesicule endocytosis
    PATHWAY
    metabolism other
    signaling signal transduction
    phosphate metabolism
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein GRB2
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS