Symbol
| BID
| contributors: mct/pgu - updated : 18-09-2015
|
HGNC name
| BH3 interacting domain death agonist
|
HGNC id
| 1050
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
constitutional
|  
|  
|  
| loss of function
|
loss of BID function impaired the ability of NOD2 but not TLR3 to trigger tissue repair responses upon injury | |
Variant & Polymorphism
|
| |
Candidate gene
Marker
Therapy target
|
System | Type | Disorder | Pubmed |
cancer | reproductive | breast | |
with its substrate CTSB were shown to be molecular links between apoptosis and autophagy in breast cancer MCF-7 cells exposed to the cytostatic drug, camptothecin |
| | | |
| Bid-/- mice are unresponsive to local or systemic exposure to NOD agonists or their protective effect in experimental colitis |