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FLASH GENE

Symbol

SEMA3C

contributors: mct/npt - updated : 30-10-2017

HGNC name	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
HGNC id	10725

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --over   in the synovial tissue of rheumatoid arthritis and osteoarthritis tumoral     --other   aberrant expression of SEMA3C is correlated with poor prognosis of pancreatic ductal adenocarcinoma (PDAC) patients and promotes tumor growth and metastasis by activating ERK1/2 signaling pathway

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS