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FLASH GENE

Symbol

CDKL5

contributors: mct/npt - updated : 28-01-2017

HGNC name	cyclin-dependent kinase-like 5
HGNC id	11411

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

ISSX , EIEE2

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional       loss of function leading to severe neurodevelopmental disorders constitutional       loss of function absence or reduction of CDKL5 kinase functions have a greater impact on the nervous system than a gain of activity

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS