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FLASH GENE

Symbol

CAT

contributors: mct - updated : 19-10-2020

HGNC name	catalase
HGNC id	1516

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

CAT

Susceptibility

to essential hypertension to noise-induced hearing loss

Variant & Polymorphism

Candidate gene	neurocognitive sequelae associated with radiation exposure can be reduced by overexpression of Mitochondrial CAT, operating through a mechanism involving the preservation of neuronal morphology
Marker
Therapy target

ANIMAL & CELL MODELS

mice devoid of catalase develop an obese, pre-diabetic phenotype