Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | NDUFS2 | contributors: mct - updated : 28-08-2008 |
HGNC name | NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) |
HGNC id | 7708 |
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Corresponding disease |
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Location | 1q23 Physical location : 161.169.104 - 161.184.182 | ||
Synonym name | |||
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Synonym symbol(s) | NUCM, CI-49kD | ||
EC.number | 1.6.99.3, 1.6.5.3 |
DNA |
TYPE | functioning gene |
STRUCTURE | 15.00 kb 15 Exon(s) |
Genomic sequence alignment details |
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10 Kb 5' upstream gene genomic sequence study |
MAPPING | cloned | Y | linked | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | ubiquitous |
constitutive of |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||
organ(s) |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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secondary structure | forty different subunits |
HOMOLOGY |
interspecies | homolog to murine T26a5.3 |
Homologene |
FAMILY |
CATEGORY | enzyme , transport carrier |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,organelle,mitochondria,inner |
basic FUNCTION |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
text | iron sulfur electron transfer carrier |
PATHWAY |
metabolism |
signaling |
a component | component of the complex I multisubunit enzyme of the oxidative phosphorylation (OXPHOS) |
INTERACTION |
DNA |
RNA |
small molecule | metal binding, |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | NDUFS2 |
related resource | MITOP database |
Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |